The Kolmogorov-Smirnov test was applied for analysis of variance of all continuous variables. Neutropenia was defined as an absolute neutrophil count 450,000/μL, respectively. A value of 10 g/dL, and severe anemia if the hemoglobin level was ≤10 g/dL. Furthermore, Hispanics with thrombocytosis were found to have a lower mortality risk compared to non-Hispanic Caucasians with thrombocytosis (HR=0.60 95% CI: 0.44–0.81). However, African-Americans (non-Hispanic Blacks) with either thrombocytopenia or thrombocytosis were at significantly lower risk compared to non-Hispanic Caucasians (HR=0.82 95% CI: 0.69–0.96 and HR=0.70 95% CI: 0.53–0.94, respectively). This effect persisted across all ethnic groups. A significant association with shorter overall survival was found for both thrombocytopenia (HR=1.45 95% CI: 1.36–1.56) and thrombocytosis (HR=1.75 95% CI: 1.56–1.97) when compared to the survival of patients with normal platelet counts. The prevalence of thrombocytopenia and thrombocytosis was examined in a large inner city outpatient population of 36,262 individuals aged ≥65 years old. Even though alterations in platelet counts are presumed to be detrimental, their impact on the survival of patients has not been studied in large cohorts.
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